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Its chemical construction offers promising insights into its capability to give pain reduction with no adverse consequences typically associated with opioids.Conolidine has been the topic of scientific experiments, which include 1 posted in Character Chemistry in 2011, which proposed it may be a promising analgesic according to checks in mice. Anot… Read More

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Most just lately, it has been discovered that conolidine and the above derivatives act within the atypical chemokine receptor three (ACKR3. Expressed in very similar places as classical opioid receptors, it binds to some big range of endogenous opioids. Contrary to most opioid receptors, this receptor acts to be a scavenger and doesn't activate a n… Read More